164 Association between atopic dermatitis and celiac disease: A systematic review and meta-analysis
نویسندگان
چکیده
Atopic Dermatitis (AD) is one of the most prevalent complex chronic inflammatory skin diseases worldwide and has been associated with many different autoimmune disorders. Celiac disease (CD), an immune-mediated gluten-enteropathy linked dermatitis herpetiformis (DH), recently among these To understand relationship between diseases, we performed first meta-analysis looking at association CD in AD patients. A systematic review PubMed, Cochrane Central, Embase, Web Science was on all studies prior to February 26, 2021 for keywords related CD. Observational data that examined two were included. then conducted using Review Manager, version 5.4. 9 1904 articles screened included this meta-analysis. Analysis demonstrated a significant adult patients having increased odds (OR: 2.25 [95% CI, 1.69-2.99], p < .05). Pediatric also had 1.80 1.48-2.19], The when stratifying by sex, men 2.54 2.29-2.80], .05) women 2.00 1.63-2.47], CD; individuals DH (OR 9.77 8.21-11.61], bi-directional found, as 1.42-3.58], This shows strong age patients, It possible papers found no connection bowel complaints under systems not included, however positive relationships suggest potential shared pathophysiological basis processes should be focus future studies.
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2022
ISSN: ['1523-1747', '0022-202X']
DOI: https://doi.org/10.1016/j.jid.2022.05.171